PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17201164-0	2006	Inhibition of pancreatic and lung adenocarcinoma cell survival by curcumin is associated with increased apoptosis, down-regulation of COX-2 and EGFR and inhibition of Erk1/2 activity.	Curcumin	66-74	epidermal growth factor receptor	Homo sapiens	144-148	
17201164-2	2006	Other studies indicated that epidermal growth factor receptor (EGFR) is also inhibited by curcumin in vitro and in vivo.	Curcumin	90-98	epidermal growth factor receptor	Homo sapiens	29-61	
17201164-2	2006	Other studies indicated that epidermal growth factor receptor (EGFR) is also inhibited by curcumin in vitro and in vivo.	Curcumin	90-98	epidermal growth factor receptor	Homo sapiens	63-67	
17201164-4	2006	Our aim was to evaluate whether the curcumin inhibitory effect on the survival of cancer cells is associated with simultaneous down-regulation of COX-2 and EGFR and inhibition of Erk1/2 (extra-cellular signal regulated kinase) signaling pathway.	Curcumin	36-44	epidermal growth factor receptor	Homo sapiens	156-160	
17201164-10	2006	In the p34 and PC-14 cells, curcumin decreased COX-2, EGFR and p-Erk1/2 expressions in a dose-dependent manner.	Curcumin	28-36	epidermal growth factor receptor	Homo sapiens	54-58	
17201164-12	2006	CONCLUSION: Curcumin co-inhibited COX-2 and EGFR expression and decreased Erk1/2 activity.	Curcumin	12-20	epidermal growth factor receptor	Homo sapiens	44-48