PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17176117-4 2006 Sir3p self-associates extensively in moderate salt and at micromolar protein concentrations producing a broad range of oligomers that sediment from 8 to in excess of 85 S. These results provide new insight into Sir3p domain organization and quaternary structure and support a nucleosome bridging model for Sir3p-dependent regulation of chromatin architecture. Salts 46-50 chromatin-silencing protein SIR3 Saccharomyces cerevisiae S288C 0-5