PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17138749-8 2006 Small-animal PET revealed rapid, specific, and prominent uptake of (64)Cu-DOTA-VEGF(121) in small U87MG tumors (high VEGFR2 expression) but significantly lower and sporadic uptake in large U87MG tumors (low VEGFR2 expression). 1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid 71-78 kinase insert domain receptor Homo sapiens 117-123 17138749-8 2006 Small-animal PET revealed rapid, specific, and prominent uptake of (64)Cu-DOTA-VEGF(121) in small U87MG tumors (high VEGFR2 expression) but significantly lower and sporadic uptake in large U87MG tumors (low VEGFR2 expression). 1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid 71-78 kinase insert domain receptor Homo sapiens 207-213 17138749-10 2006 Blocking experiments, immunofluorescence staining, and western blot confirmed the VEGFR specificity of (64)Cu-DOTA-VEGF(121). 1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid 107-114 kinase insert domain receptor Homo sapiens 82-87 17138749-11 2006 CONCLUSION: Successful demonstration of the ability of (64)Cu-DOTA-VEGF(121) to visualize VEGFR expression in vivo may allow for clinical translation of this radiopharmaceutical for imaging tumor angiogenesis and guiding antiangiogenic treatment, especially patient selection and treatment monitoring of VEGFR-targeted cancer therapy. 1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid 62-66 kinase insert domain receptor Homo sapiens 90-95 17138749-11 2006 CONCLUSION: Successful demonstration of the ability of (64)Cu-DOTA-VEGF(121) to visualize VEGFR expression in vivo may allow for clinical translation of this radiopharmaceutical for imaging tumor angiogenesis and guiding antiangiogenic treatment, especially patient selection and treatment monitoring of VEGFR-targeted cancer therapy. 1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid 62-66 kinase insert domain receptor Homo sapiens 304-309