PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17125255-1 2006 The sulfamide analogue of the antiepileptic drug topiramate is a 210 times less potent inhibitor of isozyme II of the zinc enzyme carbonic anhydrase (CA, EC 4.2.1.1) compared to topiramate but effectively inhibits isozymes CA VA, VB, VII, XIII, and XIV (KI in the range of 21-35 nM). fusarubin 4-13 carbonic anhydrase 5A Homo sapiens 223-228