PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17035026-0	2007	Modifications of the pyroglutamic acid and histidine residues in thyrotropin-releasing hormone (TRH) yield analogs with selectivity for TRH receptor type 2 over type 1.	Pyrrolidonecarboxylic Acid	21-38	thyrotropin releasing hormone	Homo sapiens	65-94	
17035026-0	2007	Modifications of the pyroglutamic acid and histidine residues in thyrotropin-releasing hormone (TRH) yield analogs with selectivity for TRH receptor type 2 over type 1.	Pyrrolidonecarboxylic Acid	21-38	thyrotropin releasing hormone	Homo sapiens	96-99	
17035026-0	2007	Modifications of the pyroglutamic acid and histidine residues in thyrotropin-releasing hormone (TRH) yield analogs with selectivity for TRH receptor type 2 over type 1.	Pyrrolidonecarboxylic Acid	21-38	thyrotropin releasing hormone	Homo sapiens	136-139	
17035026-3	2007	For example, the most selective agonist of the series 13, in which pGlu is replaced with the pAad and histidine residue is substituted at the N-1 position with an isopropyl group, was found to activate TRH-R2 with a potency (EC(50)=1.9microM) but did not activate TRH-R1 (potency>100 microM); that is, exhibited >51-fold greater selectivity for TRH-R2 versus TRH-R1.	Pyrrolidonecarboxylic Acid	67-71	thyrotropin releasing hormone	Homo sapiens	202-205