PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17015027-1 2007 Nicotinic acetylcholine receptors (nAChR) are expressed on non-neuronal cell types, including normal bronchial epithelial cells, and nicotine has been reported to cause Akt activation in cultured normal airway cells. Nicotine 133-141 AKT serine/threonine kinase 1 Homo sapiens 169-172 17015027-11 2007 Akt was also phosphorylated in NSCLC cells after exposure to nicotine; this effect was inhibited by the PI3K inhibitor LY294002 and antagonists to the neuronal-type nAChR, but not to the muscle-type receptor. Nicotine 61-69 AKT serine/threonine kinase 1 Homo sapiens 0-3 17015027-13 2007 273T cells also showed greater activation of p44/42 MAPK than of Akt in response to nicotine. Nicotine 84-92 AKT serine/threonine kinase 1 Homo sapiens 65-68