PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17004712-8 2006 To determine whether the carboxamide oxygen or the piperidine nitrogen of the C-3 substituent may be the interaction site for K3.28(192), we designed, synthesized, and evaluated a new set of analogues of 1 (3-6, Chart 1) in which modifications only to the C-3 substituent of 1 have been made. Nitrogen 62-70 complement C3 Homo sapiens 78-81