PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16979119-0	2006	Inhibition of IL-8 release from CFTR-deficient lung epithelial cells following pre-treatment with fenretinide.	Fenretinide	98-109	CF transmembrane conductance regulator	Homo sapiens	32-36	
16979119-4	2006	As fenretinide is a ceramide up-regulating drug that inhibits the activation of the pro-inflammatory transcriptional factor, nuclear factor (NF)-kappaB, the impact of fenretinide on unstimulated and tumor necrosis factor (TNF)-alpha stimulated production of NF-kappaB-dependent interleukin (IL)-8 was studied in immortalized wild-type (non-CF; 9HTEo-) and mutant DeltaF508 CFTR (CF; CFTE29o-) tracheal epithelial cells.	Fenretinide	3-14	CF transmembrane conductance regulator	Homo sapiens	340-342	
16979119-4	2006	As fenretinide is a ceramide up-regulating drug that inhibits the activation of the pro-inflammatory transcriptional factor, nuclear factor (NF)-kappaB, the impact of fenretinide on unstimulated and tumor necrosis factor (TNF)-alpha stimulated production of NF-kappaB-dependent interleukin (IL)-8 was studied in immortalized wild-type (non-CF; 9HTEo-) and mutant DeltaF508 CFTR (CF; CFTE29o-) tracheal epithelial cells.	Fenretinide	3-14	CF transmembrane conductance regulator	Homo sapiens	373-377	
16979119-7	2006	Although fenretinide treatment was associated with a higher intracellular ceramide content in the mutant DeltaF508 CFTR cells, the fenretinide-mediated decrease in IL-8 secretion was not consistently explained by changes in the intracellular content of this sphingolipid.	Fenretinide	9-20	CF transmembrane conductance regulator	Homo sapiens	115-119