PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16951146-1 2006 Growth factor activation of the phosphatidylinositol 3-kinase (PI3K)-AKT pathway has been shown to activate the estrogen receptor (ER) alpha and to mediate tamoxifen resistance in breast cancer. Tamoxifen 156-165 AKT serine/threonine kinase 1 Homo sapiens 69-72