PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16945918-2	2006	Here we show that despite the absence of these events, caspase-9 activation is essential for cephalostatin 1-induced apoptosis.	cephalostatin I	93-108	caspase 9	Homo sapiens	55-64	
16945918-3	2006	Cephalostatin 1 initiates a rapid endoplasmic reticulum stress response characterized by phosphorylation of eukaryotic initiation factor-2 alpha-subunit and increased expression of the chaperone immunoglobulin heavy chain-binding protein GRP78 as well as the transcription factor C/EBP homologous protein (CHOP)/GADD153.	cephalostatin I	0-15	heat shock protein family A (Hsp70) member 5	Homo sapiens	238-243	
16945918-3	2006	Cephalostatin 1 initiates a rapid endoplasmic reticulum stress response characterized by phosphorylation of eukaryotic initiation factor-2 alpha-subunit and increased expression of the chaperone immunoglobulin heavy chain-binding protein GRP78 as well as the transcription factor C/EBP homologous protein (CHOP)/GADD153.	cephalostatin I	0-15	DNA damage inducible transcript 3	Homo sapiens	280-304	
16945918-3	2006	Cephalostatin 1 initiates a rapid endoplasmic reticulum stress response characterized by phosphorylation of eukaryotic initiation factor-2 alpha-subunit and increased expression of the chaperone immunoglobulin heavy chain-binding protein GRP78 as well as the transcription factor C/EBP homologous protein (CHOP)/GADD153.	cephalostatin I	0-15	DNA damage inducible transcript 3	Homo sapiens	306-310	
16945918-3	2006	Cephalostatin 1 initiates a rapid endoplasmic reticulum stress response characterized by phosphorylation of eukaryotic initiation factor-2 alpha-subunit and increased expression of the chaperone immunoglobulin heavy chain-binding protein GRP78 as well as the transcription factor C/EBP homologous protein (CHOP)/GADD153.	cephalostatin I	0-15	DNA damage inducible transcript 3	Homo sapiens	312-319	
16945918-4	2006	Cephalostatin 1 activates apoptosis signal-regulating kinase 1 and c-Jun N-terminal kinase (JNK).	cephalostatin I	0-15	mitogen-activated protein kinase kinase kinase 5	Homo sapiens	26-62	
16945918-4	2006	Cephalostatin 1 activates apoptosis signal-regulating kinase 1 and c-Jun N-terminal kinase (JNK).	cephalostatin I	0-15	mitogen-activated protein kinase 8	Homo sapiens	67-90	
16945918-4	2006	Cephalostatin 1 activates apoptosis signal-regulating kinase 1 and c-Jun N-terminal kinase (JNK).	cephalostatin I	0-15	mitogen-activated protein kinase 8	Homo sapiens	92-95	
16945918-6	2006	Importantly, the endoplasmic reticulum-associated caspase-4 is required and as shown by biochemical and genetic inhibition experiments, acts upstream of caspase-9 in cephalostatin-induced apoptosis.	cephalostatin	166-179	caspase 4	Homo sapiens	50-59	
16945918-6	2006	Importantly, the endoplasmic reticulum-associated caspase-4 is required and as shown by biochemical and genetic inhibition experiments, acts upstream of caspase-9 in cephalostatin-induced apoptosis.	cephalostatin	166-179	caspase 9	Homo sapiens	153-162