PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16928811-3 2006 In the present study, we investigated the roles of extracellular signal-regulated kinase (ERK) and c-Jun-NH(2)-kinase (JNK) in the regulation of phenethyl isothiocyanate (PEITC)-induced and Nrf2-dependent ARE activity and ARE-driven heme oxygenase-1 (HO-1) gene expression in PC-3 cells. phenethyl isothiocyanate 145-169 mitogen-activated protein kinase 1 Homo sapiens 51-88 16928811-3 2006 In the present study, we investigated the roles of extracellular signal-regulated kinase (ERK) and c-Jun-NH(2)-kinase (JNK) in the regulation of phenethyl isothiocyanate (PEITC)-induced and Nrf2-dependent ARE activity and ARE-driven heme oxygenase-1 (HO-1) gene expression in PC-3 cells. phenethyl isothiocyanate 145-169 mitogen-activated protein kinase 1 Homo sapiens 90-93 16928811-3 2006 In the present study, we investigated the roles of extracellular signal-regulated kinase (ERK) and c-Jun-NH(2)-kinase (JNK) in the regulation of phenethyl isothiocyanate (PEITC)-induced and Nrf2-dependent ARE activity and ARE-driven heme oxygenase-1 (HO-1) gene expression in PC-3 cells. phenethyl isothiocyanate 171-176 mitogen-activated protein kinase 1 Homo sapiens 51-88 16928811-3 2006 In the present study, we investigated the roles of extracellular signal-regulated kinase (ERK) and c-Jun-NH(2)-kinase (JNK) in the regulation of phenethyl isothiocyanate (PEITC)-induced and Nrf2-dependent ARE activity and ARE-driven heme oxygenase-1 (HO-1) gene expression in PC-3 cells. phenethyl isothiocyanate 171-176 mitogen-activated protein kinase 1 Homo sapiens 90-93 16928811-10 2006 Taken together, these results strongly suggest a model in which PEITC treatment of PC-3 cells activates ERK and JNK, which, in turn, phosphorylate Nrf2 and induce its translocation to the nucleus. phenethyl isothiocyanate 64-69 mitogen-activated protein kinase 1 Homo sapiens 104-107