PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1691363-2 1990 The proarrhythmic action of isoproterenol was primarily the result of a beta 1-receptor-mediated tachycardia rather than via a free radical-mediated process, since it was prevented competitively by the beta 1-receptor antagonist metoprolol, but not by the free radical scavengers mannitol, superoxide dismutase, and catalase. Isoproterenol 28-41 catalase Rattus norvegicus 316-324