PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16897987-10 2006 It will be essential to prove that the combination of S-1 plus CPT-11 can replace the combination of infusional 5-FU and LV plus CPT-11 without negatively affecting efficacy and toxicity. Irinotecan 129-135 proteasome 26S subunit, non-ATPase 1 Homo sapiens 54-57