PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16820206-4 2007 We present here the first case in the literature with MDS/MPD syndrome, sole 5q- anomaly and thrombocytosis in which bortezomib administration normalized platelet count, produced a major erythroid response, and reduced levels of interleukin-6 (IL-6) and TNF-alpha while increased levels of IL-4 in the bone marrow plasma. Bortezomib 117-127 interleukin 6 Homo sapiens 229-242 16820206-4 2007 We present here the first case in the literature with MDS/MPD syndrome, sole 5q- anomaly and thrombocytosis in which bortezomib administration normalized platelet count, produced a major erythroid response, and reduced levels of interleukin-6 (IL-6) and TNF-alpha while increased levels of IL-4 in the bone marrow plasma. Bortezomib 117-127 interleukin 6 Homo sapiens 244-248