PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16797122-0	2006	Aquaporin-4 knockout regulated cocaine-induced behavior and neurochemical changes in mice.	Cocaine	31-38	aquaporin 4	Mus musculus	0-11	
16797122-5	2006	The results reveal that AQP4 deletion attenuated locomotor activity in acute and repeated cocaine exposure mice, and induced a decrease of extracellular dopamine and glutamate levels in the nucleus accumbens (NAc), a brain region known to be critically involved in the addictive properties of cocaine.	Cocaine	90-97	aquaporin 4	Mus musculus	24-28	
16797122-5	2006	The results reveal that AQP4 deletion attenuated locomotor activity in acute and repeated cocaine exposure mice, and induced a decrease of extracellular dopamine and glutamate levels in the nucleus accumbens (NAc), a brain region known to be critically involved in the addictive properties of cocaine.	Cocaine	293-300	aquaporin 4	Mus musculus	24-28	
16797122-6	2006	Therefore, AQP4 may play a role in regulating extracellular cocaine-induced dopamine and glutamate release in the brain reward center, and in turn AQP4 deletion may attenuate cocaine reinforcement and dependence.	Cocaine	60-67	aquaporin 4	Mus musculus	11-15