PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16781858-4 2007 Pretreatment with 100 microM EPA and DHA significantly decreased lipopolysaccharide (LPS)-stimulated THP-1 macrophage tumor necrosis factor (TNF) alpha, interleukin (IL) 1beta and IL-6 production (P<.02), compared to control cells. Docosahexaenoic Acids 37-40 interleukin 1 beta Homo sapiens 153-175 16781858-5 2007 Both EPA and DHA reduced TNF-alpha, IL-1beta and IL-6 mRNA expression. Docosahexaenoic Acids 13-16 interleukin 1 beta Homo sapiens 36-44 16781858-7 2007 Furthermore, a low dose (25 microM) of DHA had a greater inhibitory effect than that of EPA on macrophage IL-1beta (P<.01 and P<.04, respectively) and IL-6 (P<.003 and P<.003, respectively) production following 0.01 and 0.1 microg/ml LPS stimulation. Docosahexaenoic Acids 39-42 interleukin 1 beta Homo sapiens 106-114