PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16757730-7 2006 Candesartan treatment from the onset of obstruction attenuated the reduction in GFR (3.1 +/- 0.4 vs. 1.7 +/- 0.3 ml.min(-1).kg(-1)) and partially prevented the reduction in the expression of AQP2 (66 +/- 21 vs. 13 +/- 2%, n = 7; P < 0.05), NaPi-2 (84 +/- 6 vs. 57 +/- 10%, n = 7; P < 0.05), and NKCC2 (89 +/- 12 vs. 46% +/- 11, n = 7; P < 0.05). candesartan 0-11 aquaporin 2 Rattus norvegicus 191-195 16757730-10 2006 In conclusion, candesartan prevents dysregulation of AQP2, sodium transporters, and development of polyuria seen in BUO. candesartan 15-26 aquaporin 2 Rattus norvegicus 53-57