PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16751250-1 2006 We develop a model of tyrosine phosphorylation and activation of the T-cell receptor (TCR) by localization to regions of close membrane-membrane proximity (close contact) that physically exclude tyrosine phosphatases such as CD45. Tyrosine 22-30 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 69-84 16751250-1 2006 We develop a model of tyrosine phosphorylation and activation of the T-cell receptor (TCR) by localization to regions of close membrane-membrane proximity (close contact) that physically exclude tyrosine phosphatases such as CD45. Tyrosine 22-30 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 86-89