PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16614850-6 2007 The addition of ATRA also exhibited additional inhibitory effects on ALDH activity and increased 4-HC toxicity when added to single siRNA aimed at one of the enzymes. Tretinoin 16-20 aldehyde dehydrogenase 1 family member A1 Homo sapiens 69-73 16614850-7 2007 On the other hand, ATRA had minimal and insignificant additional inhibitory effects on ALDH enzyme activity when added to a combination of siRNAs against both enzymes, but still increased 4-HC toxicity beyond that seen with RNAi-mediated inhibition of both enzymes together. Tretinoin 19-23 aldehyde dehydrogenase 1 family member A1 Homo sapiens 87-91