PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16567507-7 2006 In diabetic PPARalpha-knockout mice, renal disease with accompanying albuminuria, glomerular sclerosis, and mesangial area expansion was more severe than in diabetic wild-type mice (P < 0.05) and was accompanied by increased levels of serum free fatty acids and triglycerides (P < 0.01). Fatty Acids, Nonesterified 244-260 peroxisome proliferator activated receptor alpha Mus musculus 12-21 16567507-12 2006 Taken together, PPARalpha deficiency appears to aggravate the severity of diabetic nephropathy through an increase in extracellular matrix formation, inflammation, and circulating free fatty acid and triglyceride concentrations. Fatty Acids, Nonesterified 180-195 peroxisome proliferator activated receptor alpha Mus musculus 16-25