PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16567414-0	2006	Tannic acid, a potent inhibitor of epidermal growth factor receptor tyrosine kinase.	Tannins	0-11	epidermal growth factor receptor	Homo sapiens	35-67	
16567414-2	2006	In the present study, tannic acid was found to strongly inhibit tyrosine kinase activity of epidermal growth factor receptor (EGFr) in vitro (IC50 = 323 nM).	Tannins	22-33	epidermal growth factor receptor	Homo sapiens	92-124	
16567414-2	2006	In the present study, tannic acid was found to strongly inhibit tyrosine kinase activity of epidermal growth factor receptor (EGFr) in vitro (IC50 = 323 nM).	Tannins	22-33	epidermal growth factor receptor	Homo sapiens	126-130	
16567414-4	2006	The inhibition of EGFr tyrosine kinase by tannic acid was competitive with respect to ATP and non-competitive with respect to peptide substrate.	Tannins	42-53	epidermal growth factor receptor	Homo sapiens	18-22	
16567414-5	2006	In cultured cells, growth factor-induced tyrosine phosphorylation of growth factor receptors, including EGFr, platelet-derived growth factor receptor, and basic fibroblast growth factor receptor, was inhibited by tannic acid.	Tannins	213-224	epidermal growth factor receptor	Homo sapiens	104-108	
16567414-9	2006	The molecular modeling study suggested that tannic acid could be docked into the ATP binding pockets of either EGFr or insulin receptor.	Tannins	44-55	epidermal growth factor receptor	Homo sapiens	111-115	
16567414-10	2006	These results demonstrate that tannic acid is an in vitro potent inhibitor of EGFr tyrosine kinase.	Tannins	31-42	epidermal growth factor receptor	Homo sapiens	78-82