PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16458528-4	2006	Here, we assessed the effect of FK506 on the expression of TGF-beta1, TbetaR-I, TbetaR-II, fibronectin (FN) and plasminogen activator inhibitor type-1 (PAI-1) in MCs.	Tacrolimus	32-37	transforming growth factor beta 1	Homo sapiens	59-68	
16458528-7	2006	Compared to untreated controls, FK506 stimulated TGF-beta1 mRNA (maximum at 8 h, 100 ng/mL: 2.13+/-0.15-fold, P<0.005) and protein expression (maximum at 96 h, 100 ng/mL: 1.96+/-0.29-fold, P<0.005).	Tacrolimus	32-37	transforming growth factor beta 1	Homo sapiens	49-58	
16458528-10	2006	These results indicate that, comparable to CsA, FK506 induced glomerulosclerosis is also due to a direct effect on mesangial matrix production, which is at least in part mediated via up-regulation of TGF-beta1 expression.	Tacrolimus	48-53	transforming growth factor beta 1	Homo sapiens	200-209