PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16418063-0 2005 Styrene monomer primarily induces CYP2B1 mRNA in rat liver. Styrene 0-7 cytochrome P450, family 2, subfamily b, polypeptide 1 Rattus norvegicus 34-40 16418063-3 2005 The amount of CYP2B1 mRNA was significantly increased, 47-fold compared with controls, suggesting that this CYP is the primary cytochrome P450 in rats exposed to styrene. Styrene 162-169 cytochrome P450, family 2, subfamily b, polypeptide 1 Rattus norvegicus 14-20 16418063-5 2005 Western blot analysis also indicated that the protein levels of CYP2B1, CYP2B2, CYP2E1 and CYP1A2 showed clear increases after styrene treatment, corresponding to their mRNA expression. Styrene 127-134 cytochrome P450, family 2, subfamily b, polypeptide 1 Rattus norvegicus 64-70 16418063-11 2005 The results demonstrate that CYP2B1 is the primarily induced CYP form by styrene treatment to rats at acute toxic level. Styrene 73-80 cytochrome P450, family 2, subfamily b, polypeptide 1 Rattus norvegicus 29-35