PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16407535-3	2006	The levels of dopamine and its major metabolites in the nucleus accumbens were markedly increased by the microinjection of orexin A and orexin B into the VTA.	Dopamine	14-22	hypocretin	Mus musculus	123-131	
16407535-3	2006	The levels of dopamine and its major metabolites in the nucleus accumbens were markedly increased by the microinjection of orexin A and orexin B into the VTA.	Dopamine	14-22	hypocretin	Mus musculus	136-144	
16407535-6	2006	Furthermore, the increased level of dialysate dopamine produced by morphine in the mouse brain was significantly decreased by deletion of the prepro-orexin gene.	Dopamine	46-54	hypocretin	Mus musculus	142-155	
16407535-7	2006	These findings provide new evidence that orexin-containing neurons in the VTA are directly implicated in the rewarding effect and hyperlocomotion induced by morphine through activation of the mesolimbic dopamine pathway in rodents.	Dopamine	203-211	hypocretin	Mus musculus	41-47