PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16385087-5	2006	Investigation of potential signaling pathways demonstrated that metformin diminished IL-1beta-induced activation and nuclear translocation of nuclear factor-kappa B (NF-kappaB) in SMCs.	Metformin	64-73	nuclear factor kappa B subunit 1	Homo sapiens	142-164	
16385087-5	2006	Investigation of potential signaling pathways demonstrated that metformin diminished IL-1beta-induced activation and nuclear translocation of nuclear factor-kappa B (NF-kappaB) in SMCs.	Metformin	64-73	nuclear factor kappa B subunit 1	Homo sapiens	166-175	
16385087-9	2006	CONCLUSIONS: These data suggest that metformin can exert a direct vascular anti-inflammatory effect by inhibiting NF-kappaB through blockade of the PI3K-Akt pathway.	Metformin	37-46	nuclear factor kappa B subunit 1	Homo sapiens	114-123