PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16332238-0 2005 Effect of cyclosporin A on the expression of inducible nitric oxide synthase in the gingiva of rats. Cyclosporine 10-23 nitric oxide synthase 2 Rattus norvegicus 45-76 16332238-8 2005 Significantly greater iNOS enzyme activities were detected in lung and gingival tissues obtained from CsA-treated animals than from control animals. Cyclosporine 102-105 nitric oxide synthase 2 Rattus norvegicus 22-26 16332238-9 2005 In addition, cells positively staining for iNOS were clearly observed in both gingival and lung tissues obtained from the CsA-treated animals by immunohistochemistry, whereas a few stained cells were found in those from the control group. Cyclosporine 122-125 nitric oxide synthase 2 Rattus norvegicus 43-47 16332238-11 2005 CONCLUSIONS: The effect of CsA on gingival iNOS expression was evaluated in rats for 4 weeks. Cyclosporine 27-30 nitric oxide synthase 2 Rattus norvegicus 43-47 16332238-12 2005 A greater iNOS expression in the gingiva was observed after CsA therapy by both enzyme activities and immunohistochemica staining. Cyclosporine 60-63 nitric oxide synthase 2 Rattus norvegicus 10-14 16332238-13 2005 Therefore, we suggest that CsA can increase gingival iNOS expression, which may play an important role in cyclosporin-induced gingival overgrowth. Cyclosporine 27-30 nitric oxide synthase 2 Rattus norvegicus 53-57 16332238-13 2005 Therefore, we suggest that CsA can increase gingival iNOS expression, which may play an important role in cyclosporin-induced gingival overgrowth. Cyclosporine 106-117 nitric oxide synthase 2 Rattus norvegicus 53-57