PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16290312-0 2005 IGF-I protects cortical neurons against ceramide-induced apoptosis via activation of the PI-3K/Akt and ERK pathways; is this protection independent of CREB and Bcl-2? Ceramides 40-48 AKT serine/threonine kinase 1 Homo sapiens 95-98 16290312-5 2005 Ceramide decreases Akt phosphorylation during apoptotic process whereas a simultaneous treatment with IGF-I increases Akt phosphorylation. Ceramides 0-8 AKT serine/threonine kinase 1 Homo sapiens 19-22