PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16239602-1 2006 The anti cancer drug methyl N-(4"-(9-acridinylamino)-3-methoxy-phenyl) methane sulfonamide (mAMSA) targets human DNA topoisomerase IIbeta. Amsacrine 92-97 DNA topoisomerase II beta Homo sapiens 113-137 16239602-3 2006 Random mutagenesis of human DNA topoisomerase IIbeta cDNA, followed by selection in yeast for resistance to mAMSA, identified betaP732L. Amsacrine 108-113 DNA topoisomerase II beta Homo sapiens 28-52