PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16190759-0 2005 A novel series of non-carboxylic acid, non-hydantoin inhibitors of aldose reductase with potent oral activity in diabetic rat models: 6-(5-chloro-3-methylbenzofuran-2-sulfonyl)-2H-pyridazin-3-one and congeners. Hydantoins 43-52 aldo-keto reductase family 1 member B1 Rattus norvegicus 67-83 16190759-1 2005 Discovery of a highly selective, potent, and safe non-carboxylic acid, non-hydantoin inhibitor of aldose reductase (AR) capable of potently blocking the excess glucose flux through the polyol pathway that prevails under diabetic conditions has been a long-standing challenge. Hydantoins 75-84 aldo-keto reductase family 1 member B1 Rattus norvegicus 98-114 16190759-1 2005 Discovery of a highly selective, potent, and safe non-carboxylic acid, non-hydantoin inhibitor of aldose reductase (AR) capable of potently blocking the excess glucose flux through the polyol pathway that prevails under diabetic conditions has been a long-standing challenge. Hydantoins 75-84 aldo-keto reductase family 1 member B1 Rattus norvegicus 116-118