PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16181459-2 2005 SLOS is caused by mutations in the DHCR7 gene which encodes 7-dehydrocholesterol reductase, an enzyme that catalyses the final step in cholesterol biosynthesis. Cholesterol 69-80 7-dehydrocholesterol reductase Homo sapiens 35-40