PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16168844-9 2005 Western blot analysis demonstrated that celecoxib downregulated the expression of Ku70 protein and inhibited the kinase activity of DNA-PKcs, which are involved in the double-stranded DNA-break repair machinery. Celecoxib 40-49 protein kinase, DNA-activated, catalytic subunit Homo sapiens 132-140 16168844-10 2005 By EMSA, it was further shown that celecoxib reduced DNA-binding activity of Ku/DNA-PKcs protein complex. Celecoxib 35-44 protein kinase, DNA-activated, catalytic subunit Homo sapiens 80-88