PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16103452-2	2005	Thus, deficient folate status has been hypothesized to be associated primarily with ER gene-negative breast tumors, but data relating folate intake to breast cancer risk according to ER status are sparse.	Folic Acid	16-22	estrogen receptor 1	Homo sapiens	84-86	
16103452-5	2005	Higher total folate intake was significantly associated with lower risk of developing ER- but not ER+ breast cancer; the multivariable relative risks (RR) and 95% confidence intervals (95% CI) comparing the highest to the lowest quintile were 0.81 (0.66-0.99) for ER- tumors and 1.00 (0.89-1.14) for ER+ tumors.	Folic Acid	13-19	estrogen receptor 1	Homo sapiens	86-88	
16103452-6	2005	The inverse association between total folate intake and ER- breast cancer was mainly present among women consuming at least 15 g/d of alcohol (multivariable RR, 0.46; 95% CI,=0.25-0.86; top versus bottom quintile).	Folic Acid	38-44	estrogen receptor 1	Homo sapiens	56-58	
16103452-7	2005	These findings support the hypothesis that higher folate intake reduces the risk of developing ER- breast cancer.	Folic Acid	50-56	estrogen receptor 1	Homo sapiens	95-97