PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16080463-0	2005	Differential effect of anti-apoptotic genes Bcl-xL and c-FLIP on sensitivity of MCF-7 breast cancer cells to paclitaxel and docetaxel.	Docetaxel	124-133	BCL2 like 1	Homo sapiens	44-50	
16080463-6	2005	Caspase 8 and 9 activities were measured in cells overexpressing Bcl-xL or c-FLIP exposed to docetaxel and paclitaxel using fluorescent substrate cleavage assay.	Docetaxel	93-102	BCL2 like 1	Homo sapiens	65-71	
16080463-7	2005	RESULTS: MCF-7 cells overexpressing Bcl-xL but not TRAF-1, cIAP-2 or Mn-SOD were less sensitive to both paclitaxel and docetaxel compared to vector-transfected control cells.	Docetaxel	119-128	BCL2 like 1	Homo sapiens	36-42	
16080463-9	2005	2-Methoxyantimycin A3, a chemical inhibitor of Bcl-xL, sensitized Bcl-xL-overexpressing cells to paclitaxel and docetaxel, which suggests the drugs that inhibit Bcl-xL activity can be used as sensitizers to taxanes.	Docetaxel	112-121	BCL2 like 1	Homo sapiens	47-53	
16080463-9	2005	2-Methoxyantimycin A3, a chemical inhibitor of Bcl-xL, sensitized Bcl-xL-overexpressing cells to paclitaxel and docetaxel, which suggests the drugs that inhibit Bcl-xL activity can be used as sensitizers to taxanes.	Docetaxel	112-121	BCL2 like 1	Homo sapiens	66-72	
16080463-9	2005	2-Methoxyantimycin A3, a chemical inhibitor of Bcl-xL, sensitized Bcl-xL-overexpressing cells to paclitaxel and docetaxel, which suggests the drugs that inhibit Bcl-xL activity can be used as sensitizers to taxanes.	Docetaxel	112-121	BCL2 like 1	Homo sapiens	66-72	
16080463-12	2005	CONCLUSION: Because c-FLIP inhibits the extrinsic pathway of cell death whereas Bcl-xL inhibits the intrinsic pathway of cell death, these results suggest that overexpression of anti-apoptotic genes that inhibit either the extrinsic or intrinsic cell death pathways can reduce sensitivity of cancer cells to paclitaxel, whereas anti-apoptotic genes that inhibit only the intrinsic pathway reduce sensitivity to docetaxel.	Docetaxel	411-420	BCL2 like 1	Homo sapiens	80-86