PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16036432-11 2005 RyR (type 1 and 2) is a major component of the intracellular calcium channel, which mediates calcium-induced calcium release. Calcium 61-68 ryanodine receptor 2 Homo sapiens 0-3 16036432-11 2005 RyR (type 1 and 2) is a major component of the intracellular calcium channel, which mediates calcium-induced calcium release. Calcium 93-100 ryanodine receptor 2 Homo sapiens 0-3 16036432-11 2005 RyR (type 1 and 2) is a major component of the intracellular calcium channel, which mediates calcium-induced calcium release. Calcium 93-100 ryanodine receptor 2 Homo sapiens 0-3 16036432-12 2005 FKBP12, which is an endogenous ligand for RyR, stabilizes the calcium channels preventing calcium leakage in the absence of receptor activation. Calcium 62-69 ryanodine receptor 2 Homo sapiens 42-45 16036432-12 2005 FKBP12, which is an endogenous ligand for RyR, stabilizes the calcium channels preventing calcium leakage in the absence of receptor activation. Calcium 90-97 ryanodine receptor 2 Homo sapiens 42-45 16036432-14 2005 Further study of the correlation between RyR and FKBP12 should contribute to clarifying the mechanisms of neurodegeneration in MND, including calcium-induced neuronal loss. Calcium 142-149 ryanodine receptor 2 Homo sapiens 41-44