PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16018822-8 2005 The effect of sirolimus on activation of mammalian target of rapamycin (mTOR) was measured by phosphorylation of the substrate p70s6k at T389, and activation of RhoA was measured by pull-down assay. Sirolimus 14-23 ribosomal protein S6 kinase B1 Homo sapiens 127-133