PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15982677-1	2005	Acrylamide, an animal carcinogen and germ cell mutagen present at low (ppm) levels in heated carbohydrate-containing foodstuffs, is oxidized by cytochrome P4502E1 (CYP2E1) to the epoxide glycidamide, which is believed to be responsible for the mutagenic and carcinogenic activity of acrylamide.	Acrylamide	0-10	cytochrome P450, family 2, subfamily e, polypeptide 1	Mus musculus	164-170	
15982677-1	2005	Acrylamide, an animal carcinogen and germ cell mutagen present at low (ppm) levels in heated carbohydrate-containing foodstuffs, is oxidized by cytochrome P4502E1 (CYP2E1) to the epoxide glycidamide, which is believed to be responsible for the mutagenic and carcinogenic activity of acrylamide.	Acrylamide	283-293	cytochrome P450, family 2, subfamily e, polypeptide 1	Mus musculus	164-170	
15982677-9	2005	In those experiments, dose-related increases in dominant lethal mutations were detected in uterine contents of female mice mated to acrylamide-treated wild-type males but not CYP2E1-null males, clearly implicating CYP2E1-mediated formation of glycidamide in the induction of genetic damage in male germ cells.	Acrylamide	132-142	cytochrome P450, family 2, subfamily e, polypeptide 1	Mus musculus	214-220	
15982677-15	2005	These results support the hypothesis that genetic damage in somatic and germ cells of mice-treated with acrylamide is dependent upon metabolism of the parent compound by CYP2E1.	Acrylamide	104-114	cytochrome P450, family 2, subfamily e, polypeptide 1	Mus musculus	170-176