PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15962312-4 2005 The cellular levels of MetAP-2 enzyme were measured after MetAP-2 siRNA treatment and found to decrease over time from 4 to 96 h, while rapid and complete depletion of MetAP-2 enzyme activity was observed after 4 h treatment with two pharmacological inhibitors of MetAP-2, PPI-2458 and fumagillin. fumagillin 286-296 methionyl aminopeptidase 2 Homo sapiens 23-30 15962312-5 2005 When HUVEC and A549 cells were treated simultaneously with MetAP-2 siRNA and PPI-2458, or fumagillin, which irreversibly inhibit MetAP-2 enzyme activity, no additive effect on maximum growth inhibition was observed. fumagillin 90-100 methionyl aminopeptidase 2 Homo sapiens 129-136