PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15955561-1 2005 FK506 and rapamycin are immunosuppressant drugs that disrupt the interaction of FK506-binding proteins (FKBPs) with ryanodine receptors (RyR1), which form homotetrameric Ca2+ release channels in the sarcoplasmic reticulum (SR) of skeletal muscle. Tacrolimus 0-5 ryanodine receptor 1 Homo sapiens 137-141 15955561-1 2005 FK506 and rapamycin are immunosuppressant drugs that disrupt the interaction of FK506-binding proteins (FKBPs) with ryanodine receptors (RyR1), which form homotetrameric Ca2+ release channels in the sarcoplasmic reticulum (SR) of skeletal muscle. Tacrolimus 80-85 ryanodine receptor 1 Homo sapiens 137-141