PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15860571-2 2005 In the present study, we investigated whether 6-ethyl chenodeoxycholic acid (6-ECDCA or INT-747), a semisynthetic derivative of chenodeoxycholic acid (CDCA), modulates tissue metalloproteinase inhibitor (TIMP)-1 and matrix metalloprotease (MMP)-2 expression/activity in HSCs and in the liver of rats rendered cirrhotic by 4-week administration of CCl(4). obeticholic acid 46-75 matrix metallopeptidase 2 Rattus norvegicus 216-246