PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15738419-7 2005 We propose that the underlying mechanisms of nicotine"s detrimental side effects on a range of crucial defensive reflexes involve loss of function of nAChR subtypes, possibly via activity-dependent desensitization. Nicotine 45-53 cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus 150-155