PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1569208-4 1992 To determine the intracellular signals generated in hypoxic or ischemic cells that trigger HSF activation, we examined the effects of glucose deprivation and the metabolic inhibitor rotenone on DNA-binding activity of HSF in cultured C2 myogenic cells grown under normoxic conditions. Rotenone 182-190 interleukin 6 Homo sapiens 218-221 1569208-8 1992 However, 2 x 10(-4) M rotenone induced DNA binding of HSF within 30 min, in association with a fall in ATP to 30% of control levels, and a fall in pHi from 7.3 to 6.9. Rotenone 22-30 interleukin 6 Homo sapiens 54-57