PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15684063-2	2005	The constitutive androstane receptor (CAR) and pregnane X receptor (PXR) are xenobiotic nuclear receptors that coordinate protective hepatic responses to potentially toxic stimuli, including bile acids.	Bile Acids and Salts	191-201	nuclear receptor subfamily 1, group I, member 3	Mus musculus	4-36	
15684063-2	2005	The constitutive androstane receptor (CAR) and pregnane X receptor (PXR) are xenobiotic nuclear receptors that coordinate protective hepatic responses to potentially toxic stimuli, including bile acids.	Bile Acids and Salts	191-201	nuclear receptor subfamily 1, group I, member 3	Mus musculus	38-41	
15684063-2	2005	The constitutive androstane receptor (CAR) and pregnane X receptor (PXR) are xenobiotic nuclear receptors that coordinate protective hepatic responses to potentially toxic stimuli, including bile acids.	Bile Acids and Salts	191-201	nuclear receptor subfamily 1, group I, member 2	Mus musculus	47-66	
15684063-2	2005	The constitutive androstane receptor (CAR) and pregnane X receptor (PXR) are xenobiotic nuclear receptors that coordinate protective hepatic responses to potentially toxic stimuli, including bile acids.	Bile Acids and Salts	191-201	nuclear receptor subfamily 1, group I, member 2	Mus musculus	68-71	
15684063-4	2005	Hepatic damage from bile acid accumulation was increased in both CAR knockout (CARKO) and PXR knockout mice, but bile acid concentrations were lower in CARKO mice.	Bile Acids and Salts	20-29	nuclear receptor subfamily 1, group I, member 3	Mus musculus	65-68	
15684063-4	2005	Hepatic damage from bile acid accumulation was increased in both CAR knockout (CARKO) and PXR knockout mice, but bile acid concentrations were lower in CARKO mice.	Bile Acids and Salts	20-29	nuclear receptor subfamily 1, group I, member 2	Mus musculus	90-93	
15684063-5	2005	High-density lipoprotein (HDL) cholesterol was elevated in CARKO mice, and serum total cholesterol increased less in CARKO or PXR knockout mice than WT mice after BDL.	Cholesterol	87-98	nuclear receptor subfamily 1, group I, member 2	Mus musculus	126-129	
15684063-8	2005	These results demonstrate that CAR and PXR influence cholesterol metabolism and bile acid synthesis, as well as multiple detoxification pathways, and suggest their potential role as therapeutic targets for the treatment of cholestasis and lipid disorders.	Cholesterol	53-64	nuclear receptor subfamily 1, group I, member 3	Mus musculus	31-34	
15684063-8	2005	These results demonstrate that CAR and PXR influence cholesterol metabolism and bile acid synthesis, as well as multiple detoxification pathways, and suggest their potential role as therapeutic targets for the treatment of cholestasis and lipid disorders.	Cholesterol	53-64	nuclear receptor subfamily 1, group I, member 2	Mus musculus	39-42	
15684063-8	2005	These results demonstrate that CAR and PXR influence cholesterol metabolism and bile acid synthesis, as well as multiple detoxification pathways, and suggest their potential role as therapeutic targets for the treatment of cholestasis and lipid disorders.	Bile Acids and Salts	80-89	nuclear receptor subfamily 1, group I, member 3	Mus musculus	31-34	
15684063-8	2005	These results demonstrate that CAR and PXR influence cholesterol metabolism and bile acid synthesis, as well as multiple detoxification pathways, and suggest their potential role as therapeutic targets for the treatment of cholestasis and lipid disorders.	Bile Acids and Salts	80-89	nuclear receptor subfamily 1, group I, member 2	Mus musculus	39-42