PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15676214-0	2005	Anti-CD33 monoclonal antibodies enhance the cytotoxic effects of cytosine arabinoside and idarubicin on acute myeloid leukemia cells through similarities in their signaling pathways.	Cytarabine	65-85	CD33 molecule	Homo sapiens	5-9	
15676214-5	2005	RESULTS: CD33 ligation induced a significant increase in ara-C- or IDA- but not VP-16-or Bryostatin-mediated inhibition of proliferation and colony formation.	Cytarabine	57-62	CD33 molecule	Homo sapiens	9-13	
15676214-8	2005	Combined treatment of AML cells by ara-C or IDA with anti-CD33 mAb resulted in higher levels of SHP-1 phosphorylation.	Cytarabine	35-40	CD33 molecule	Homo sapiens	58-62	
15676214-10	2005	CONCLUSION: These data suggest that combined incubation of leukemia cells with anti-CD33 mAb and ara-C or IDA, but not VP-16 or Bryostatin, independently triggers similar events in the downstream signaling cascade, and therefore leads to additive antiproliferative effects and enhanced cytotoxicity.	Cytarabine	97-102	CD33 molecule	Homo sapiens	84-88