PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15667273-0 2005 Nar1p, a conserved eukaryotic protein with similarity to Fe-only hydrogenases, functions in cytosolic iron-sulphur protein biogenesis. Iron 102-106 iron-sulfur cluster assembly protein NAR1 Saccharomyces cerevisiae S288C 0-5 15667273-2 2005 Previously, we have shown that Nar1p is an Fe-S protein and that assembly of its co-factors depends on the mitochondrial Fe-S cluster biosynthesis apparatus. Iron 43-47 iron-sulfur cluster assembly protein NAR1 Saccharomyces cerevisiae S288C 31-36 15667273-3 2005 Using functional studies in vivo, we demonstrated that Nar1p has an essential role in the maturation of cytosolic and nuclear, but not of mitochondrial, Fe-S proteins. Iron 153-157 iron-sulfur cluster assembly protein NAR1 Saccharomyces cerevisiae S288C 55-60 15667273-4 2005 Here we provide further spectroscopic evidence that Nar1p possesses two Fe-S clusters. Iron 72-76 iron-sulfur cluster assembly protein NAR1 Saccharomyces cerevisiae S288C 52-57 15667273-5 2005 We also show that Nar1p is required for Fe-S cluster assembly on the P-loop NTPase Nbp35p, another newly identified component of the cytosolic Fe-S protein assembly machinery. Iron 40-44 iron-sulfur cluster assembly protein NAR1 Saccharomyces cerevisiae S288C 18-23 15667273-5 2005 We also show that Nar1p is required for Fe-S cluster assembly on the P-loop NTPase Nbp35p, another newly identified component of the cytosolic Fe-S protein assembly machinery. Iron 40-44 Fe-S cluster-binding ATPase Saccharomyces cerevisiae S288C 83-89 15667273-5 2005 We also show that Nar1p is required for Fe-S cluster assembly on the P-loop NTPase Nbp35p, another newly identified component of the cytosolic Fe-S protein assembly machinery. Iron 143-147 iron-sulfur cluster assembly protein NAR1 Saccharomyces cerevisiae S288C 18-23 15667273-5 2005 We also show that Nar1p is required for Fe-S cluster assembly on the P-loop NTPase Nbp35p, another newly identified component of the cytosolic Fe-S protein assembly machinery. Iron 143-147 Fe-S cluster-binding ATPase Saccharomyces cerevisiae S288C 83-89