PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15666830-1 2004 We have previously reported that the protein kinase C ligand 12-O-tetradecanoyphorbol-13-acetate (TPA) inhibited the angiotensin II (AII) stimulated CYP11B2 gene expression in the adrenocortical H295R cell line. Tetradecanoylphorbol Acetate 98-101 angiotensinogen Homo sapiens 117-131 15666830-1 2004 We have previously reported that the protein kinase C ligand 12-O-tetradecanoyphorbol-13-acetate (TPA) inhibited the angiotensin II (AII) stimulated CYP11B2 gene expression in the adrenocortical H295R cell line. Tetradecanoylphorbol Acetate 98-101 angiotensinogen Homo sapiens 133-136 15666830-7 2004 Taken together these results suggest that TPA inhibits the AII-dependent activation of CYP11B2 via the p44/42 MAPK signaling pathway leading to an increase of the level of nuclear JunB. Tetradecanoylphorbol Acetate 42-45 angiotensinogen Homo sapiens 59-62