PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15590691-0	2005	Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2.	Threonine	18-27	mitogen-activated protein kinase kinase kinase 7	Homo sapiens	109-159	
15590691-0	2005	Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2.	Threonine	18-27	mitogen-activated protein kinase kinase kinase 7	Homo sapiens	161-165	
15590691-0	2005	Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2.	Threonine	18-27	mitogen-activated protein kinase kinase kinase 7	Homo sapiens	201-205	
15590691-2	2005	Here, we characterized the molecular mechanisms of cellular stress-induced TAK1 activation, focusing mainly on the phosphorylation of TAK1 at Thr-187 and Ser-192 in the activation loop.	Threonine	142-145	mitogen-activated protein kinase kinase kinase 7	Homo sapiens	75-79	
15590691-2	2005	Here, we characterized the molecular mechanisms of cellular stress-induced TAK1 activation, focusing mainly on the phosphorylation of TAK1 at Thr-187 and Ser-192 in the activation loop.	Threonine	142-145	mitogen-activated protein kinase kinase kinase 7	Homo sapiens	134-138	
15590691-2	2005	Here, we characterized the molecular mechanisms of cellular stress-induced TAK1 activation, focusing mainly on the phosphorylation of TAK1 at Thr-187 and Ser-192 in the activation loop.	Serine	154-157	mitogen-activated protein kinase kinase kinase 7	Homo sapiens	75-79	
15590691-3	2005	Thr-187 and Ser-192 are conserved among species from Caenorhabditis elegans to human, and their replacement with Ala resulted in inactivation of TAK1.	Threonine	0-3	mitogen-activated protein kinase kinase kinase 7	Homo sapiens	145-149	
15590691-3	2005	Thr-187 and Ser-192 are conserved among species from Caenorhabditis elegans to human, and their replacement with Ala resulted in inactivation of TAK1.	Serine	12-15	mitogen-activated protein kinase kinase kinase 7	Homo sapiens	145-149	
15590691-3	2005	Thr-187 and Ser-192 are conserved among species from Caenorhabditis elegans to human, and their replacement with Ala resulted in inactivation of TAK1.	Alanine	113-116	mitogen-activated protein kinase kinase kinase 7	Homo sapiens	145-149	
15590691-4	2005	Immunoblotting with a novel phospho-TAK1 antibody revealed that TNF-alpha significantly induced the phosphorylation of endogenous TAK1 at Thr-187, and subsequently the phosphorylated forms of TAK1 rapidly disappeared.	Threonine	138-141	mitogen-activated protein kinase kinase kinase 7	Homo sapiens	36-40	
15590691-4	2005	Immunoblotting with a novel phospho-TAK1 antibody revealed that TNF-alpha significantly induced the phosphorylation of endogenous TAK1 at Thr-187, and subsequently the phosphorylated forms of TAK1 rapidly disappeared.	Threonine	138-141	tumor necrosis factor	Homo sapiens	64-73	
15590691-4	2005	Immunoblotting with a novel phospho-TAK1 antibody revealed that TNF-alpha significantly induced the phosphorylation of endogenous TAK1 at Thr-187, and subsequently the phosphorylated forms of TAK1 rapidly disappeared.	Threonine	138-141	mitogen-activated protein kinase kinase kinase 7	Homo sapiens	130-134	
15590691-4	2005	Immunoblotting with a novel phospho-TAK1 antibody revealed that TNF-alpha significantly induced the phosphorylation of endogenous TAK1 at Thr-187, and subsequently the phosphorylated forms of TAK1 rapidly disappeared.	Threonine	138-141	mitogen-activated protein kinase kinase kinase 7	Homo sapiens	130-134	
15590691-5	2005	Intermolecular autophosphorylation of Thr-187 was essential for TAK1 activation.	Threonine	38-41	mitogen-activated protein kinase kinase kinase 7	Homo sapiens	64-68	
15590691-7	2005	Furthermore, SB203580 and p38alpha small interfering RNA enhanced TNF-alpha-induced Thr-187 phosphorylation as well as TAK1 kinase activity, indicating that the phosphorylation is affected by p38alpha/TAB1/TAB2-mediated feedback control of TAK1.	SB 203580	13-21	tumor necrosis factor	Homo sapiens	66-75	
15590691-7	2005	Furthermore, SB203580 and p38alpha small interfering RNA enhanced TNF-alpha-induced Thr-187 phosphorylation as well as TAK1 kinase activity, indicating that the phosphorylation is affected by p38alpha/TAB1/TAB2-mediated feedback control of TAK1.	SB 203580	13-21	mitogen-activated protein kinase kinase kinase 7	Homo sapiens	119-123	
15590691-7	2005	Furthermore, SB203580 and p38alpha small interfering RNA enhanced TNF-alpha-induced Thr-187 phosphorylation as well as TAK1 kinase activity, indicating that the phosphorylation is affected by p38alpha/TAB1/TAB2-mediated feedback control of TAK1.	SB 203580	13-21	mitogen-activated protein kinase 14	Homo sapiens	192-200	
15590691-7	2005	Furthermore, SB203580 and p38alpha small interfering RNA enhanced TNF-alpha-induced Thr-187 phosphorylation as well as TAK1 kinase activity, indicating that the phosphorylation is affected by p38alpha/TAB1/TAB2-mediated feedback control of TAK1.	SB 203580	13-21	mitogen-activated protein kinase kinase kinase 7	Homo sapiens	240-244	
15590691-7	2005	Furthermore, SB203580 and p38alpha small interfering RNA enhanced TNF-alpha-induced Thr-187 phosphorylation as well as TAK1 kinase activity, indicating that the phosphorylation is affected by p38alpha/TAB1/TAB2-mediated feedback control of TAK1.	Threonine	84-87	mitogen-activated protein kinase 14	Homo sapiens	26-34	
15590691-7	2005	Furthermore, SB203580 and p38alpha small interfering RNA enhanced TNF-alpha-induced Thr-187 phosphorylation as well as TAK1 kinase activity, indicating that the phosphorylation is affected by p38alpha/TAB1/TAB2-mediated feedback control of TAK1.	Threonine	84-87	tumor necrosis factor	Homo sapiens	66-75	
15590691-7	2005	Furthermore, SB203580 and p38alpha small interfering RNA enhanced TNF-alpha-induced Thr-187 phosphorylation as well as TAK1 kinase activity, indicating that the phosphorylation is affected by p38alpha/TAB1/TAB2-mediated feedback control of TAK1.	Threonine	84-87	mitogen-activated protein kinase 14	Homo sapiens	192-200	
15590691-7	2005	Furthermore, SB203580 and p38alpha small interfering RNA enhanced TNF-alpha-induced Thr-187 phosphorylation as well as TAK1 kinase activity, indicating that the phosphorylation is affected by p38alpha/TAB1/TAB2-mediated feedback control of TAK1.	Threonine	84-87	mitogen-activated protein kinase kinase kinase 7	Homo sapiens	240-244	
15590691-8	2005	These results indicate critical roles of Thr-187 phosphorylation in the stress-induced rapid and transient activation of TAK1 in a signaling complex containing TAB1 and TAB2.	Threonine	41-44	mitogen-activated protein kinase kinase kinase 7	Homo sapiens	121-125