PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15557278-3	2005	We now show that: 1) Trio and another Rac GEF (Tiam1) act by inducing GDP to GTP exchange on prenylated Rac1-GDP and that our earlier assertion that activation is GTP-independent is explained by contamination of p67phox preparations with GTP and/or ATP.	Guanosine Diphosphate	70-73	Ras protein specific guanine nucleotide releasing factor 1	Homo sapiens	42-45	
15557278-3	2005	We now show that: 1) Trio and another Rac GEF (Tiam1) act by inducing GDP to GTP exchange on prenylated Rac1-GDP and that our earlier assertion that activation is GTP-independent is explained by contamination of p67phox preparations with GTP and/or ATP.	Guanosine Diphosphate	109-112	Ras protein specific guanine nucleotide releasing factor 1	Homo sapiens	42-45	
15557278-6	2005	4) The ability of ATP to support GEF-induced oxidase activation is explained by ATP serving as a gamma-phosphoryl donor for a membrane-localized nucleoside diphosphate kinase (NDPK), converting GDP to GTP.	Guanosine Diphosphate	194-197	Ras protein specific guanine nucleotide releasing factor 1	Homo sapiens	33-36	
15557278-9	2005	7) Free GDP is derived exclusively by dissociation from prenylated Rac1-GDP, mediated by GEF.	Guanosine Diphosphate	8-11	Ras protein specific guanine nucleotide releasing factor 1	Homo sapiens	89-92	
15557278-10	2005	NDPK and GEF appear to be functionally linked in the sense that the availability of GDP, serving as substrate for NDPK, is dependent on the level of activity of GEF.	Guanosine Diphosphate	84-87	Ras protein specific guanine nucleotide releasing factor 1	Homo sapiens	9-12	
15557278-10	2005	NDPK and GEF appear to be functionally linked in the sense that the availability of GDP, serving as substrate for NDPK, is dependent on the level of activity of GEF.	Guanosine Diphosphate	84-87	Ras protein specific guanine nucleotide releasing factor 1	Homo sapiens	161-164