PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15494464-0 2005 Epidermal growth factor receptor inhibition by tyrphostin 51 induces apoptosis in luteinized granulosa cells. Tyrphostins 47-57 epidermal growth factor receptor Homo sapiens 0-32 15494464-2 2005 Our objective is to test the hypothesis that, in human luteinized granulosa cells, epidermal growth factor (EGF) works through the MAPK signaling pathway and inhibition of EGF receptor by a specific tyrosine kinase inhibitor, tyrphostin 51, will inhibit the activation of MAPK and induce apoptosis. Tyrphostins 226-236 epidermal growth factor receptor Homo sapiens 172-184 15494464-4 2005 Blockage of EGF receptor by tyrphostin 51 reduced the MAPK activity and inhibited phosphorylation and nuclear translocation of activated MAPK. Tyrphostins 28-38 epidermal growth factor receptor Homo sapiens 12-24