PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15454119-0	2004	Nicotine could augment adhesion molecule expression in human endothelial cells through macrophages secreting TNF-alpha, IL-1beta.	Nicotine	0-8	interleukin 1 beta	Homo sapiens	120-128	
15454119-7	2004	The results showed TNF-alpha, IL-1beta could reach the peak with 0.06mM nicotine treated for 24 and 12 h on Ana-1, respectively, but IL-8 and IFN-gamma had no significant alter.	Nicotine	72-80	interleukin 1 beta	Homo sapiens	30-38	
15454119-11	2004	In conclusion, our findings suggest that nicotine could augment macrophages releasing TNF-alpha and IL-1beta, furthermore TNF-alpha and IL-1beta could up-regulate the expression of adhesion molecule and increase adhesion of monocytes to HUVECs.	Nicotine	41-49	interleukin 1 beta	Homo sapiens	100-108