PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15336974-9 2004 We review the importance of calstabin2 for RyR2 function and excitation-contraction coupling, and discuss new observations that implicate dysregulation of calstabin2 binding as a central mechanism for abnormal calcium cycling in heart failure and triggered arrhythmias. Calcium 210-217 FKBP prolyl isomerase 1B Homo sapiens 155-165